Testing Platelet Activation With a Shear-Dependent Platelet Function Test Versus Aggregation-Based Tests
نویسندگان
چکیده
منابع مشابه
Testing platelet activation with a shear-dependent platelet function test versus aggregation-based tests: relevance for monitoring long-term glycoprotein IIb/IIIa inhibition.
BACKGROUND Tests developed to monitor glycoprotein (GP) IIb/IIIa blockade do not properly reflect platelet function in vivo and need a baseline (pretreatment) value. Because GP IIb/IIIa is essential in platelet aggregation and thrombosis under shear conditions, a flow-dependent approach to monitor its inhibition can be used. METHODS AND RESULTS We compared a test based on flow-dependent plate...
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Authorship Statement M.J. Maxwell designed and performed the majority of the research and experiments, and co-wrote the paper with S.P. Jackson. E. Westein collected and analysed data and assisted in manuscript preparation. W.S. Nesbitt collected data for figures 1 and 7. S. Giuliano collected data for figures 1 and 7. S.M. Dopheide collected data for figure 1. S.P. Jackson designed research, p...
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ژورنال
عنوان ژورنال: Circulation
سال: 2001
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.103.11.1488